No hay vida sin muerte ni placer sin pesar
- There is no life without death or pleasure without regret.
- There is no life without death or pleasure without sorrow.

El tiempo es oro.
- The time is gold.
- Time is money. [or] Time is precious.

¿Qué te pasa, calabaza?
- What's up, pumpkin?
- What's up buttercup!

No me importa un pepino.
- I don't care a cucumber.
- It doesn't matter to me. I don't give a rip.

En el peligro se conoce al amigo
- In danger the friend is known.
- A friend in need is a friend indeed. (You know who your friends are when you are in danger and need help.)

Estar entre la espada y la pared
- To be between the sword and the wall
- To be between a rock and a hard place

El mundo es un pañuelo.
- The world is a handkerchief.
- It's a small world.

El hábito no hace al monje.
- The habit doesn't make the monk.
- Clothes do not make the man.

El saber no ocupa lugar.
- Knowledge doesn't occupy a place.
- Knowledge is no burden.

Más vale prevenir que curar.
- It's worth more to prevent than to cure.
- A stitch in time saves nine.

Cada loco con su tema
- Every crazy person with their issue
- Everybody has their own way of doing things.

Dormir a pierna suelta
- To sleep with a loose leg
- To sleep like a log

Tener memoria de pez
- To have the memory of a fish
- To have a bad memory

Ponerse las pilas
- To put on the batteries
- Wake up, pay attention, start thinking

Echar una mano
- To throw a hand
- To give a helping hand

En un abrir y cerrar de ojos:
- In the opening and closing of one's eyes
- In the blink of an eye

A rey muerto, rey puesto
- A king dies; a king takes his place.
- Out with the old, in with the new

Más vale maña que fuerza.
- Better skill than strength
- Brains over brawn/intelligence is better than physical strength.

Favor con favor se paga
- Favor with favor, it pays
- You scratch my back and I will scratch yours. / You do me a favor and I will do you a favor. / Quid pro quo

No saber ni papa de algo
- Not knowing a potato about it
- I don't have a clue about it.

Tirar/Botar la casa por la ventana
- To throw the house out of the window
- Sparing no expense

Zapatero, a tus zapatos
- Shoemaker, to your shoes
- Cobbler, stick to your last. / Mind your business.

A donde el corazón se inclina, el pie camina.
- Where the heart inclines, the foot walks.
- Where our heart leads, we follow.

El amor todo lo puede.
- Love can do it all.
- Love will find a way. / With love everything is possible.